How come supposedly dexamphetamine has a duration of action of only around 3 to 6 hours, while the expensive slow release version lisdexamfetamine has a duration of action of 12 hours, but 'lisdex' is converted to 'dex' within an hour?


While, yes, it does take extra time for the body to convert it into amphetamine, it doesn't have much to do with the actual drug.
This is adderall. It's comprised of 4 different amphetamine salts plus some inert binders to make it big enough to easily dispense and take. Your stomach acid will break down a pill in less than an hour.
This is adderall XR. It's a 24 hour slow release. It contains pretty much the exact same mix of amphetamine salts.

However, this is what is inside an adderall XR capsule. Those beads are the magic. 
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Ferruccio Steven | Program Manager | Pharmacology 2020
Larix International Pte Ltd
Contact: +65 31655042
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Email: pharmacology@medicinalchemistryconferences.com

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