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Showing posts from March, 2020

How come supposedly dexamphetamine has a duration of action of only around 3 to 6 hours, while the expensive slow release version lisdexamfetamine has a duration of action of 12 hours, but 'lisdex' is converted to 'dex' within an hour?

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While, yes, it does take extra time for the body to convert it into amphetamine , it doesn't have much to do with the actual drug. This is adderall. It's comprised of 4 different amphetamine salts plus some inert binders to make it big enough to easily dispense and take. Your stomach acid will break down a pill in less than an hour. This is adderall XR. It's a 24 hour slow release. It contains pretty much the exact same mix of amphetamine salts. However, this is what is inside an adderall XR capsule. Those beads are the magic.  For more details regarding the conference please visit :  https://medicinalchemistryconferences.com/ Regards Ferruccio Steven | Program Manager | Pharmacology 2020 Larix International Pte Ltd Contact: +65 31655042 WhatsApp: +65 3158 6820 Email: pharmacology@medicinalchemistryconferences.com

What is pharmaceutical formulation? What are the stages involved?

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Pharmaceutical formulation , in pharmaceutics, is a process in which various chemical substances, along with the active drug, are mixed to produce a final medicinal product. The word formulation is often used in a way that includes the dosage form used in the making. What Are The Stages And Timeline? Formulation studies include developing a preparation of the drug which is stable as well as acceptable to the patient. This usually involves adding the drug into a tablet or a capsule for administered drugs. It is important to differentiate that a tablet contains a variety of other potentially inert substances apart from the drug itself. Further, studies have to be done to ensure that the encapsulated drug is compatible with these other substances and will not cause harm, either direct or indirect. Preformulation stage in  pharma manufacturing  involves the characterization of a drug's physical, chemical, and mechanical properties to choose what other ingredients or excip...